Acrolein causes DNA mutations similar to those found in lung cancer.
Acrolein, one of the 4,000 constituents of tobacco cigarette smoke, has been found unexpectedly to cause DNA damage in the gene for the infamous tumor-suppressor p53, which is often disrupted by cancer. In particular, the pattern of DNA mutations caused by acrolein mimics what is often found in human lung cancer samples.
“If cigarette smoke is the weapon that causes lung cancer, then these mutations are fingerprints on the knife,” says author Moon-shong Tang of New York University School of Medicine, in Tuxedo. Tang was also involved in identifying another cigarette-smoke component that can induce such mutations: a metabolite of a polycyclic hydrocarbon called benzoapyrene. Acrolein is present in cigarette smoke in levels of up to 1,000 times greater than benzo pyrene.
Acrolein alkylates guanine residues in DNA, causing a pattern of DNA damage that is “remarkably similar to that observed in the commonly mutated p53 gene isolated from lung tumors in smokers,” comments Stephen S. Hecht of the University of Minnesota Cancer Center.
“These results of cigarette smoking is scary” he says.
This is where E-cigarettes comes to the rescue of a trillion suffering smokers. The Electronic cigarette contains no tar, carbon monoxide, or harmful toxins like the ones that are found in normal cigarettes and are smokefree. Normal tobacco cigarettes have over 4,000 harmful poisons that are not found in electric cigarettes. Advantages of electronic cigarettes:
You may actually smoke less
When you smoke a tobacco cigarette you feel obligated to smoke the entire cigarette. The e-cigarette allows you to take a few puffs and put it away for another time. You naturally smoke less because of this.
Electric cigarettes are a lot less expensive than smoking regular cigarettes. The traditional pack of cigarettes costs around Rs 100. One electronic cigarette cartridge is equal to nearly a full pack and only costs Rs 20.
No second hand smoke
No more worrying about second-hand smoke that bothers the non-smokers around you. The Electronic cigarette gives off NO second hand smoke. Second hand smoke has been reported to be worse than smoking. Now, you can keep your loved ones safe by using electronic cigarettes. The vapor that is released looks like smoke, but is only water vapor that disappears in a few seconds.
Electronic cigarettes give off no smoke! They only produce water vapor. There are no pollutants being released into the air every time you take a puff. It’s the ‘green’ alternative to traditional cigarettes.
No Smoke smell
No more smoke smelling hair and clothes. When you use an electronic cigarette you breath out pure water vapor which contains no odor. I have used mine in the homes of non-smokers with no complaints.
Smoke where ever and when ever you want
Electronic cigarettes allow you to puff where ever you are so you can get your nicotine fix in places where smoking is not permitted. Now you can calm your cravings at work, in the restaurant, at the bar, or airport without having to step out for a ‘smoking break’.
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No Ashtrays, no burns
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E-cigs are a great alternative to traditional tobacco cigarettes.